Atopic dermatitis pathogenesis is complex, and it is not possible to identify a single biological step which would recapitulate its pathogenesis (FIG. AD1).
However, a defined number of crucial steps have been identified, whose modeling is provided by ALLTOX (FIG. AD2). The complete list of assays to evaluate a given xenobiotic for its capability to interfere with the progression of the inflammation typical of atopic dermatitis, including reference compounds as comparison, is here.
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